Which of the following is NOT a common metastatic route for Acute Lymphocytic Leukemia (ALL)?

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Acute Lymphocytic Leukemia (ALL) primarily spreads through the blood and typically involves the bone marrow, lymphatic system, and various organs. Common sites for metastasis in ALL include lymph nodes, liver, and spleen, as these sites are part of the body's lymphatic and hematologic systems.

The kidneys, while they can be involved in other malignancies, are not a common site for the metastasis of ALL. The disease usually manifests through an accumulation of lymphoblasts in the bone marrow and can lead to infiltration in organs with lymphatic tissues. The other options, being lymphatic-associated structures, facilitate the progression of leukemic cells, making them much more likely to be involved in the disease's spread. Thus, kidneys are not typically affected in this context, reinforcing the selection of this option as the one that does not fit the common metastatic pattern of ALL.

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